Chronic marijuana use may lead to higher anesthesia requirements by changing how the body processes drugs. Long-term use can increase liver enzymes, causing anesthetics to break down more quickly. It also alters brain receptor sensitivity, leading to cross-tolerance with sedatives. Lifestyle factors like smoking behavior and overall health further influence anesthesia dosing. It’s important to be honest with your anesthesia team about your medical and social history, including cannabis use 🫡.
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